Figure 7
MSI and mass spectra at 180 days post-exposure. MALDI-MS merged image of two high mannose glycan structures, tentatively assigned as Hex5HexNac4 and Hex7HexNac2, showing differential distribution in a lung sample taken at 180 days post-radiation (from R03007) in (A). The H&E stained section is shown in (B) and the MSI overlaid with the H&E section is shown in (C). Single pixel spectra and higher magnification stained sections are shown for regions of edema and mixed immune infiltration (D and blue boxes), and regions of interstitial fibrosis and immune infiltration (E and red boxes).
