Figure 4 | Scientific Reports

Figure 4

From: Increasing endogenous activity of NMDARs on GABAergic neurons increases inhibition, alters sensory processing and prevents noise-induced tinnitus

Figure 4

Infusion of M-8324 prior to noise exposure prevented tinnitus in noise exposure model. (A) Experimental procedure. (B) Pre-pulse inhibition was not altered by M-8324, compared with Veh, in noise exposure model. N = 5 mice for each group. (C) M-8324 prevented deficit in gap detection in noise exposure model. Percent of startle suppression in M-8324 group was significantly lower than that in the Veh group. Data are presented as the mean ± SEM.

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