Figure 2 | Scientific Reports

Figure 2

From: Human IDH mutant 1p/19q co-deleted gliomas have low tumor acidity as evidenced by molecular MRI and PET: a retrospective study

Figure 2

Comparison of MTRasym between 1p/19q co-deleted and non-co-deleted gliomas in T2 hyperintense lesions. (a–e) Show the comparison within all patients, WHO grade II gliomas, grade III gliomas, gliomas with oligodendroglial component, and IDH mutant gliomas, respectively. Each patient data point is represented by a dot and the violin plots represent the distribution of the patient data. In all patient cohorts, significantly lower MTRasym is observed in 1p/19q co-deleted gliomas compared to 1p/19q non-co-deleted gliomas (**, P < 0.01; ***, P < 0.001; ****, and P < 0.0001). The ROC analyses for differentiating 1p/19q co-deletion status in patients with WHO grade II and/or III gliomas using MTRasym are demonstrated in (f). The colored dots represent the optimal operating points.

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