Table 2 Background levels of E2-2,3-Q-1-S-Alb and E2-2,3-Q-4-S-Alb, and E2-3,4-Q-2-S-Alb in serum derived from women with breast cancer and healthy controls.

From: Imbalances in the disposition of estrogen and naphthalene in breast cancer patients: a potential biomarker of breast cancer risk

Adducts

Patientsa (n = 143)

Healthy controls (n = 119)

E2-2,3-Q-1-S-Alb (pmole/g-Alb)

Mean (SD)

NDb

NDb

Median

NDb

NDb

Range

NDb

NDb

E2-2,3-Q-4-S-Alb (pmole/g-Alb)

Mean (SD)

400 (258)c

204 (111)

Median

323

171

Range

61.7–1,325

48–461

E2-3,4-Q-2-S-Alb (pmole/g-Alb)

Mean (SD)

676 (338)c

66.8 (38.8)

Median

633

53.4

Range

188–1594

16.2–174

Ratio of mean levels of E2-3,4-Q-2-S-Alb to E2-2,3-Q-4-S-Alb

1.69 (1.37)c

0.330 (0.350)

  1. a, Most estrogen quinone adduct data were previously analyzed and published 35. These data are included in this table for comparison with healthy controls. b, Not detected. The limit of detection corresponds to 10 pmol/g for all adducts, assuming 10 mg protein was used for the assay. c, statistical significance, p < 0.001.
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