Table 5 The growth inhibition zones of bacteria in agar well diffusion assay in various concentrations of CoNPs, Z. clinopodioides, and Co(NO3)2.

From: RETRACTED ARTICLE: Novel green synthesis and antioxidant, cytotoxicity, antimicrobial, antidiabetic, anticholinergics, and wound healing properties of cobalt nanoparticles containing Ziziphora clinopodioides Lam leaves extract

Dilution (mg/mL)

Inhibition zone in well diffusion (mm)

Gram-positive bacteria

Gram-negative bacteria

S. typhimurium

E. coli

P. aeruginosa

S. aureus

S. pneumoniae

B. subtilis

CoNPs (64)

33.6 ± 1.14ab

36.2 ± 0.83a

38.4 ± 0.54a

38.2 ± 0.44a

39 ± 1a

40.2 ± 1.3a

CoNPs (32)

31.4 ± 0.89ab

31.2 ± 0.44ab

31.4 ± 0.89ab

31 ± 1ab

34.6 ± 0.89ab

33.8 ± 0.44ab

CoNPs (16)

24.2 ± 1.3b

26.2 ± 0.83b

26.2 ± 1.3b

27.4 ± 0.89b

25.6 ± 1.14b

29.4 ± 0.54b

CoNPs (8)

20.6 ± 0.89bc

22.4 ± 1.34bc

21.4 ± 1.34bc

24.4 ± 0.89b

22.6 ± 0.89bc

27.4 ± 0.89b

CoNPs (4)

13.4 ± 1.34c

15.6 ± 0.89bc

17.2 ± 1.3bc

18 ± 1.22bc

18.4 ± 0.54bc

21.2 ± 1.3bc

CoNPs (2)

8.2 ± 0.44c

10.4 ± 0.54c

12 ± 0c

14.2 ± 0.44c

13.2 ± 1.3c

15.4 ± 0.89bc

CoNPs (1)

0 ± 0d

0 ± 0d

8.4 ± 1.34c

9.8 ± 0.44c

10.4 ± 0.54c

12.2 ± 0.83c

Z. clinopodioides (64)

24.8 ± 0.44b

25.4 ± 0.89b

27 ± 1b

28.8 ± 0.44b

28.4 ± 0.89b

30.8 ± 1.09ab

Z. clinopodioides (32)

19.6 ± 1.14bc

21.2 ± 1.3bc

23.8 ± 0.44b

24 ± 0.7b

22.8 ± 0.44bc

27.2 ± 0.44b

Z. clinopodioides (16)

13.2 ± 0.83c

19 ± 1.22bc

20.8 ± 1.09bc

19.2 ± 0.83bc

20.4 ± 0.54bc

22.4 ± 1.34bc

Z. clinopodioides (8)

11.8 ± 1.09c

13 ± 1c

15.8 ± 1.09bc

14 ± 1.22c

17 ± 1bc

16 ± 1.22bc

Z. clinopodioides (4)

8.2 ± 0.83c

9.2 ± 1.3c

10.4 ± 1.34c

12 ± 0.7c

13.6 ± 1.14c

15.4 ± 1.34bc

Z. clinopodioides (2)

0 ± 0d

8.2 ± 0.44c

10.6 ± 1.14c

9.6 ± 0.89c

10 ± 0.7c

12 ± 1.22c

Z. clinopodioides (1)

0 ± 0d

0 ± 0d

0 ± 0d

0 ± 0d

0 ± 0d

10 ± 0c

Co(NO3)2 (64)

14.4 ± 0.54c

16.4 ± 0.89bc

18 ± 0.7bc

17 ± 1.22bc

18 ± 0.7bc

20.6 ± 0.89bc

Co(NO3)2 (32)

10.2 ± 1.3c

11.6 ± 1.14c

13 ± 0.7c

13 ± 0c

14.8 ± 0.44c

17.8 ± 0.44bc

Co(NO3)2 (16)

8.6 ± 0.89c

9.2 ± 0.83c

11.2 ± 1.3c

12.4 ± 1.34c

12.4 ± 0.54c

13.2 ± 1.3c

Co(NO3)2 (8)

0 ± 0d

8 ± 0c

10 ± 0c

10.4 ± 0.89c

11 ± 0.7c

11 ± 0.7c

Co(NO3)2 (4)

0 ± 0d

0 ± 0d

0 ± 0d

0 ± 0d

8.4 ± 0.54c

9.8 ± 0.44c

Co(NO3)2 (2)

0 ± 0d

0 ± 0d

0 ± 0d

0 ± 0d

0 ± 0d

0 ± 0d

Co(NO3)2 (1)

0 ± 0d

0 ± 0d

0 ± 0d

0 ± 0d

0 ± 0d

0 ± 0d

Distilled water

0 ± 0d

0 ± 0d

0 ± 0d

0 ± 0d

0 ± 0d

0 ± 0d

  1. Non-identical letters reveal a notable shift between the experimental groups (p ≤ 0.01).