Figure 1

Blood pressure (A) and heart rate (B) measurements during supine (pre- and post-HDBR) and HDBR. Dashed horizontal lines with shaded areas represent the mean ± s.d. of the daily measurements by MEDES staff at 7:30 am one half hour after waking and before breakfast. The box plots represent the mean (25th–50th percentile) ± range of our measurements made between 10 and 11 am in supine pre-, post-HDBR, and during HDBR. The vertical lines projecting from the horizontal line above (B) represent the supine data collected by our group that were significantly different from R0. †Data that were different from BDC12. *Data that were different from BDC02.