Figure 8
From: The HERC1 ubiquitin ligase regulates presynaptic membrane dynamics of central synapses
Electron microphotographs illustrating the main differences between control (A,C) and tbl (B,D) coated vesicles (cv) and endosomes (e). Coated vesicles and endocytic pits are most numerous in control than in tbl synaptic boutons (E, ***p = 2.559E−08; **p = 0.00936, respectively). Otherwise, endosomes were most numerous (E, **p = 0.00543) and greater (F, ***p = 0.00016) in tbl than in control presynaptic endings. The arrow in A indicates a coated vesicle integrating into an endosome. Bars = 200 nm.
