Figure 4
MEB network synchronicity is amplified by stimulation during neurogenesis and synaptogenesis. a. Representative raster plots of MEB cultures at D25 showing network synchrony by line plots of the sum of active electrodes for each time point. b. The average correlation value (χ) was calculated for active electrodes across time for an average value for each electrode, then mapped to their respective spatial position on the MEA array. c. Bar graphs representing the mean correlation value across the culture for the MEA cultures at the different days of recording. The correlation value for the culture was calculated using active electrodes during spontaneous time of each culture for each day of recording. Each point corresponds to the correlation value across electrodes for each MEA culture. (n = 3; error bar represents SEM, *p < 0.05, ANOVA with Tukey post-hoc test).
