Table 1 Clinical characteristics of the LiER and LiNR patients with bipolar disorder included in the global methylation study.

From: A DNA methylation signature discriminates between excellent and non-response to lithium in patients with bipolar disorder type 1

 

LiER

LiNR

P-value

N

15

11

 

Alda range

7–10

0–3

 

Ratio Male/Female

8/7

6/5

0.95

Age

49.85 ± 11.24

46.58 ± 6.54

0.32

BD type 1

100%

100%

 

BMI

24.48 ± 3.26

25.71 ± 3.16

0.35

Smokers yes/no

6/9

6/5

0.47

Current medication

 Li yes/no

14/1

5/6

7.6 10–3

 Anticonvulsants yes/no

3/12

5/6

0.17

 Atypical antipsychotic yes/no

0/15

7/4

3.9 10–4

 Antidepressants yes/no

3/12

4/7

0.36

 Number of psychotropic drugs 1/2/3

11/3/1

3/4/4

0.015

  1. Li lithium, ER excellent responder, NR non-responder, N number, BD bipolar disorder, BMI body mass index.
Back to article page