Table 2 Seven selected DMRs in ERs vs NRs with an AUC > 0.85.

From: A DNA methylation signature discriminates between excellent and non-response to lithium in patients with bipolar disorder type 1

DMR ID

FDR

# CpGs

Location

Gene

Mean difference in % methylation

AUC

DMR67206

5.4E−08

45

Intergenic

NA

15.99 ± 7.80

0.891

DMR24332

7.2E−12

25

Intron

LINC01237

− 9.89 ± 2.77

0.897

DMR30347

1.1E−16

44

TTS

EIF2B5/ VWA5B2

16.25 ± 5.44

0.879

DMR17107

1.7E−02

25

Exon

C2orf81

12.49 ± 5.16

0.855

DMR106540

3.6E−02

20

Intergenic

NA

11.66 ± 3.55

0.842

DMR101660

7.30E−13

15

Promoter-TSS

RALGAPA1

− 12.2 ± 3.46

0.842

DMR57278

4.1E−02

33

Intergenic

NA

− 3.48 ± 2.55

0.788

  1. For each DMR, the FDR, number of CpGs, location and associated genes are reported. The mean ± standard deviation values were computed using the DNA methylation difference (%) of individual CpG sites between ERs and NRs.
  2. NA not available.
Back to article page