Figure 8
From: Phosphate-dependent aggregation of [KL]n peptides affects their membranolytic activity

Leakage of POPC/POPG (1/2) vesicles induced by KL peptides. Panels A, B, C, were performed with a constant weight of 30 µg peptide acting on 115 µg lipids in a 1,500 µL volume. Panels D, E, F were performed with a constant molar peptide concentration of 10 µM and 100 µM lipids. (A, D) Vesicles in phosphate buffer (PB) were added to peptides in PB. (B, E) Peptides in water were added to vesicles in PB. (C, F) No PB was used, as the peptides in water were added to vesicles in PIPES buffer.