Table 3 Abnormal results of the dRVVT test depending on anticoagulant treatment.

From: Functional lupus anticoagulant testing in a large retrospective cohort of thrombosis patients with direct oral anticoagulants

Anticoagulant

Proportion of patients with abnormalities in the dRVVT, n

Controls

aPLneg

aPLlow

aPLhigh

None or discontinued

2% (34)

4% (36)

8% (14)

32% (23)

Rivaroxaban

–

66% (301)*

79% (73)*

84% (31)*

Apixaban

–

7% (7)

12% (3)

33% (5)

VKA

–

19% (107)*

27% (32)*

64% (54)*

LMWH

–

6% (14)

17% (10)

38% (13)

  1. Patients with a prolonged dRVVT screen and a dRVVT ratio > 1.2 were considered abnormal.
  2. dRVVT, dilute Russell viper venom time; LMWH, low molecular weight heparin; NS, not significant; VKA, vitamin K antagonist.
  3. *Significantly higher in comparison to the cohort with no or discontinued anticoagulants (P < 10–4 for all significantly different comparisons, calculated using the chi-squared test).
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