Table 4 Abnormal results of LA-sensitive aPTT depending on anticoagulant treatment.

From: Functional lupus anticoagulant testing in a large retrospective cohort of thrombosis patients with direct oral anticoagulants

Anticoagulant

Proportion of patients with abnormalities in the LA-sensitive aPTT, n

Controls

aPLneg

aPLlow

aPLhigh

None or discontinued

3% (47)

2% (19)

5% (9)

15% (11)

Rivaroxaban

–

2% (9)

5% (5)

54% (20)*

Apixaban

–

7% (7)

0% (0)

20% (3)

VKA

–

3% (15)

11% (13)

26% (22)

LMWH

–

5% (12)

16% (9)

32% (11)

  1. Patients with a prolonged LA-sensitive aPTT and a ratio of LA-sensitive aPTT/aPTT > 1.2 were considered abnormal.
  2. LMWH, low molecular weight heparin; VKA, vitamin K antagonist.
  3. *Significantly higher in comparison to the cohort with no or discontinued anticoagulants (P < 10–4), calculated using the chi-squared test.
Back to article page