Table 5 Repeated testing of LA positive patients using anticoagulant drugs in cohorts aPLneg, aPLlow.

From: Functional lupus anticoagulant testing in a large retrospective cohort of thrombosis patients with direct oral anticoagulants

 

Patients with anticoagulants at

LA positivea with anticoagulants

1st testing

2nd testing

Continued

Discontinued

Rivaroxaban, n

83a

50

26/50 (52%)

2/33 (6%)

VKA, n

60a

44

18/44 (41%)

1/16 (6%)

Other, n

15a

10

8/10 (80%)

0/5 (0%)

Total, n

158

104

52/104 (50%)

3/54 (6%)b

  1. dRVVT, dilute Russell viper venom time; VKA, vitamin K antagonist.
  2. aPatients with a prolonged dRVVT screen and a dRVVT ratio > 1.2, and/or a prolonged aPTT and a ratio of LA-sensitive aPTT/aPTT > 1.2.
  3. bIn the cohort aPLneg 0/40 patients with discontinued anticoagulant treatment were tested repeatedly positive for LA activity.
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