Table 1 Stability of secondary structure formed by genome of coronavirus.
From: Human SARS-CoV-2 has evolved to reduce CG dinucleotide in its open reading frames
Genus | Virus | 5′-UTR* | TSS-to-end | Virulence grade | ||
|---|---|---|---|---|---|---|
Free energy (kcal/mol) | Stability index | Free energy (kcal/mol) | Stability index | |||
Alphacoronavirus | Bat CoV CDPHE15 | − 66.8 | 92 (H) | − 8,803.5 | 99 (H) | 6 |
Bat CoV HKU10 | − 61.3 | 84 (M) | − 8,029.1 | 90 (H) | 5 | |
Cat CoV1 | − 68.8 | 95 (H) | − 7,963.0 | 89 (M) | 5 | |
Rat CoV | − 59.5 | 82 (M) | − 8,615.0 | 97 (H) | 5 | |
Mink CoV1 | − 71.2 | 98 (H) | − 7,790.4 | 88 (M) | 5 | |
Bat CoV1 | − 59.6 | 82 (M) | − 8,153.4 | 92 (H) | 5 | |
Bat CoV Sax2011 | − 66.7 | 92 (H) | − 8,815.5 | 99 (H) | 6 | |
Bat CoV SC2013 | − 57.3 | 79 (L) | − 8,712.4 | 98 (H) | 4 | |
PEDV | − 62.4 | 86 (M) | − 8,671.9 | 97 (H) | 5 | |
Bat CoV HKU2 | − 64.3 | 88 (M) | − 8,313.0 | 93 (H) | 5 | |
Human CoV NL63 | − 58.9 | 81 (M) | − 7,223.3 | 81 (M) | 4 | |
Human CoV 229E | − 55.6 | 76 (L) | − 7,982.5 | 90 (H) | 4 | |
Betacoronavirus | Human CoV HKU1 | − 43.1 | 59 (L) | − 6,864.6 | 77 (L) | 2 |
Human MERS-CoV | − 72.8 | 100 (H) | − 8,436.5 | 95 (H) | 6 | |
Human SARS-CoV | − 63.2 | 87 (M) | − 8,054.1 | 91 (H) | 5 | |
Human SARS-CoV-2 | − 62.4 | 86 (M) | − 7,860.4 | 88 (M) | 4 | |
Bat CoV ZJ2013 | − 58.9 | 81 (M) | − 8,328.2 | 94 (H) | 5 | |
Bat CoV HKU9 | − 55.2 | 76 (L) | − 8,897.8 | 100 (H) | 4 | |
Deltacoronavirus | Wigeon CoV HKU20 | − 51.8 | 71 (L) | − 8,273.2 | 93 (H) | 4 |
Bulbul CoV HKU11 | − 54.3 | 75 (L) | − 8,387.6 | 94 (H) | 4 | |
Heron CoV HKU19 | − 54.9 | 75 (L) | − 7,687.2 | 86 (M) | 3 | |
Moorhen CoV HKU21 | − 51.2 | 70 (L) | − 8,140.4 | 91 (H) | 4 | |
Gammacoronavirus | Whale CoV SW1 | − 62.8 | 86 (M) | − 8,161.3 | 92 (H) | 5 |
Turkey CoV | − 59.0 | 81 (M) | − 8,195.4 | 92 (H) | 5 | |
