Table 3 The association between admission serum ionized calcium levels and in-hospital acute kidney injury occurrence.

From: Impact of admission serum ionized calcium levels on risk of acute kidney injury in hospitalized patients

Admission serum ionized calcium level (mg/dL)

Univariate analysis

Multivariate analysis

OR (95% CI)

p

Adjusted ORa (95% CI)

P

(a) Acute kidney injury

 ≤ 4.39

1.69 (1.44–1.99)

 < 0.001

1.45 (1.21–1.74)

 < 0.001

4.40–4.59

1.49 (1.29–1.72)

 < 0.001

1.33 (1.14–1.56)

 < 0.001

4.60–4.79

1.23 (1.08–1.40)

0.002

1.13 (0.98–1.30)

0.09

4.80–4.99

1.13 (0.99–1.29)

0.07

1.07 (0.93–1.23)

0.37

5.00–5.19

1 (reference)

1 (reference)

 ≥ 5.20

1.51 (1.26–1.82)

 < 0.001

1.26 (1.04–1.54)

0.02

(b) Acute kidney injury stage 2–3

 ≤ 4.39

4.43 (3.07–6.41)

 < 0.001

2.41 (1.63–3.56)

 < 0.001

4.40–4.59

2.50 (1.73–3.60)

 < 0.001

1.75 (1.20–2.56)

0.004

4.60–4.79

1.90 (1.35–2.68)

 < 0.001

1.55 (1.09–2.21)

0.01

4.80–4.99

1.56 (1.09–2.22)

0.01

1.36 (0.95–1.95)

0.10

5.00–5.19

1 (reference)

1 (reference)

 ≥ 5.20

2.45 (1.58–3.78)

 < 0.001

1.83 (1.17–2.87)

0.008

  1. aAdjusted for age, sex, race, Charlson score, baseline glomerular filtration rate, history of coronary artery disease, hypertension, diabetes mellitus, congestive heart failure, peripheral vascular disease, stroke, admission type, admission service, principal diagnosis, use of angiotensin converting enzyme inhibitor/angiotensin receptor blocker, diuretics, non-steroidal anti-inflammatory drug, the need for vasopressor and mechanical ventilator at hospital admission, admission serum phosphate, magnesium, and albumin.