Table 3 Single ROI study vs multiple ROI study. For the multiple lesion affected patients, values obtained in multiple ROI drawing in BI were compared to the ones obtained in single ROI drawing in LIFEx. P values compared the mentioned pair of data.

From: Comparison of different automatic methods for the delineation of the total metabolic tumor volume in I–II stage Hodgkin Lymphoma

Threshold

Study type

BI (cm3)

LIFEx (cm3)

p value

Mean

Median

Range

Mean

Median

Range

BI vs LIFEx

2.5

Single ROI

250.96

203.41

9–805

249.84

189.80

9–804

0.11

Multiple ROI

247.85

197.74

9–794

0.07

41%

Single ROI

96.21

75.90

13–461

86.66

72.08

13–462

0.004

Multiple ROI

101.90

76.52

17–470

0.04

50%

Single ROI

63.10

44.20

8–384

57.82

43.62

8–384

0.004

Multiple ROI

66.06

47.14

11–393

0.007