Figure 5 | Scientific Reports

Figure 5

From: A rationally designed bicyclic peptide remodels Aβ42 aggregation in vitro and reduces its toxicity in a worm model of Alzheimer’s disease

Figure 5

Effects of DesBP on the morphology of  Zn2+-stabilised oligomers [38]. ANS fluorescence (red line) and size (grey bars) of Aβ40 oligomers at a concentration of 5 μM in the absence or in the presence of various concentrations of DesBP. Zn2+-stabilised oligomers were incubated for 2 h after addition of DesBP at room temperature. The maximum of the ThT fluorescence from the kinetic measurements is shown for comparison (orange).

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