Figure 4
From: CD122-targetted IL-2 signals cause acute and selective apoptosis of B cells in Peyer’s Patches
S4B6 IL-2C treatment does not impact IL-2 receptor expression on PP B cells. Representative staining and summary analysis of CD122 expression on CD8 T cells in control and IL-2C-treated mice in the (A) spleen and (B) PPs. Analysis of (C) CD122 and (D) CD25 expression on PP B cells. (E) Representative staining to identify viable B cells in PPs and (F) analysis of CD122 and CD25 expression on viable B cells from PPs and spleens isolated from IL-2C-treated and control mice. All data summarizes experiments with 4 mice per group. All error bars represent the standard deviation and significant differences determined with unpaired, two-tailed, students t-tests (*P < 0.05, ***P < 0.001, NS denotes no significant difference) in (A) and (B) and with ANOVA for (C), (D), and (F).
