Figure 5 | Scientific Reports

Figure 5

From: Fatty acid mimetic PBI-4547 restores metabolic homeostasis via GPR84 in mice with non-alcoholic fatty liver disease

Figure 5

Effects of PBI-4547 intervention on WATs in a HFD mouse model. (A) Representative images of H&E and Sirius red-stained WAT section and scoring of interstitial fibrosis of STD, HFD and HFD + PBI-4547 mice. (B) Evaluation of adipocyte maximum diameter and adipocyte surface area. Data are presented as mean ± SEM (n ≥ 6 per group, one-way ANOVA with Dunnett’s multicomparison test vs HFD). (C) Relative mRNA expression levels of genes related to fibrosis, inflammation, browning/thermogenesis, adipokines and glucose transporters. Geometric mean expression of qRT-PCR data was set to 1 for HFD group.

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