Figure 6
Assessment of glycemic parameters and insulin resistance in HFD-fed WT and Gpr84−/− mice. (A) Average body weight (%) of mice 0–8 weeks after beginning of treatment. (B) Oral Glucose Tolerance Test (OGTT) and area under the curve of the OGTT of mice after 6 weeks of treatment. (C) Average fasting blood glucose and fasting insulin levels of the mice after 6 weeks of treatment. (D) Insulin resistance (HOMA-IR) and glucose disposition index of mice after 6 weeks of treatment. (E) Measurements of total cholesterol, triglycerides and adiponectin levels in serum of HFD mice after 0 and 4 weeks of treatment. Data are presented as mean ± SEM (n ≥ 9 per group, one-way ANOVA with Bonferroni’s multicomparison test).
