Figure 3

Evaluation of genome wide methylation levels between C-MPNST and SCM. (a) Differential methylation heatmap of the 60 above-mentioned genes and the (b) JAK/STAT pathway genes. Y-axis and x-axis represent the genes and gene region (body vs. promoter), respectively. The methylation status is expressed through the normalized β score with a range from − 0.5 (hypomethylated/blue) to + 0.5 (hypermethylated/red).