Table 1 Parameters considered for the global sensitivity analysis. See the supplementary material for a more extensive explanation.
From: An in-silico study of cancer cell survival and spatial distribution within a 3D microenvironment
Parameter | Description |
|---|---|
a | Multiplicative coefficient of the doubling rate of the proliferant cells and of the degradation of the dead cells |
b | Multiplicative coefficient of the rate of transition between quiescency and proliferation |
c | Multiplicative coefficient of the rate of cell death |
d | Multiplicative coefficient of the rate of transition between proliferation and quiescency |
e | Multiplicative coefficient of the migration rate |
UGlu | Amount of glucose consumed by each cell in the time unit |
UO2 | Amount of oxygen consumed by each cell in the time unit |
UYM | Effect exerted by each cell on the matrix in the time uni |
s | Scale factor between the oxygen and glucose consumed by quiescent and proliferant cells |
