Figure 1 | Scientific Reports

Figure 1

From: Bone marrow mammaglobin-1 (SCGB2A2) immunohistochemistry expression as a breast cancer specific marker for early detection of bone marrow micrometastases

Figure 1

Representative pictures of the H&E and mammaglobin-1 IHC staining. (A) Positive case of metastatic invasive ductal carcinoma (IDC), the neoplastic epithelial cells forming nests in the fibrous stroma of the bone marrow (H&E, × 100). (B) Suspicious case of metastatic IDC shows hypercellularity and numerous inflammatory cells (plasma cells, histocytes and eosinophils) (H&E, × 400). (C) Suspicious case of metastatic breast carcinoma showing inflammatory infiltrates (plasma cells and eosinophils) (H&E, × 400). (D) The same case shown in C revealing brown cytoplasmic staining of mammaglobin-1 (positive stain) (Immunoperoxidase, × 400).

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