Table 4 Differences in imaging findings between MMA patients with different gender subgroups.

From: Brain MRI features of methylmalonic acidemia in children: the relationship between neuropsychological scores and MRI findings

MR imaging finding

The group by gender (N, %)

χ2

P

Male (27)

Female (10)

cerebral sulcus widened

14 (51.9)

3 (30.0)

1.403

0.288

Cerebellar atrophy

5 (18.5)

2 (20.0)

0.010

0.999

Brainstem thinning

4 (14.8)

1 (10.0)

0.145

0.704

Corpus callosum thinning

9 (33.3)

6 (60.0)

2.153

0.142

Cortical atrophy (sulcal widening)

10 (37.0)

5 (50.0)

0.509

0.476

Ventricular dilation (0–3 grade)

0

20 (74.1)

6 (60.0)

0.922

0.820

Mild

2 (7.4)

1 (10.0)

  

Moderate

1 (3.7)

1 (10.0)

  

Severe

4 (14.8)

2 (20.0)

  

Subcortical white matter change

13 (48.1)

1 (10.0)

4.515

0.034

Periventricular white matter change

0

6 (22.2)

2 (20.0)

1.456a

0.885

Mild

17 (63.0)

8 (80.0)

1.345

0.764

Moderate

3 (11.1)

0

Severe

1 (3.7)

0

Internal capsule change

2 (7.4)

2 (20.0)

1.200

0.291

Signal change consistent with focal infarct

3 (11.1)

0

1.209

0.272

Abnormal signal in basal ganglia

1

0