Figure 7 | Scientific Reports

Figure 7

From: Heteromeric Kv7.2 current changes caused by loss-of-function of KCNQ2 mutations are correlated with long-term neurodevelopmental outcomes

Figure 7

Western blotting demonstrated the protein expression in S247X, S247L, and S247W. (a) In contrast to the KCNQ2 WT, KCNQ2 protein cell-membrane expression was not present in S247X (arrow). (b) Immunostaining with the anti-KCNQ2 antibody demonstrated the HEK293 cell-membrane expression of S247L, S247W, and S247X variants. Protein expressions were lower in S247L and S247W.

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