Figure 3
Mean (± SEM). Two-way analysis of variance (ANOVA) and Bonferroni post hoc test was used. Levels of Nrf2, Gpx1, IL-6 and TNFα mRNA in hippocampus brain region in three selected strains: BXD84/RwwJ RI, BXD21/TyJ RI mice and C57BL/6 wild type as control group at 7-months-of-age (n = 6–12). (A) Levels of Nrf2 mRNA grouping by strains. (B) Levels of Gpx1 mRNA grouping by strains. (C) Levels of IL-6 mRNA grouping by strains. (D) Levels of TNFα mRNA grouping by strains (*) and (***) Statistical analyses indicate significant differences between the BXD21/TyJ RI strain and the control group and BXD84/RwwJ RI strain (p ≤ 0.001) in (C) and statistical analyses showed significant differences between the BXD21/TyJ RI strain and the control group in (D) (p ≤ 0.05).
