Table 1 Dolichol to polyprenol ratios (DOH/POH) at each stage of the P. falciparum asexual intraerythrocytic cycle.

From: Metabolomics profiling reveals new aspects of dolichol biosynthesis in Plasmodium falciparum

P. falciparum intraerythrocytic stage

DOH/POH-15

DOH/POH-16

DOH/POH-17

DOH/POH-18

DOH/POH-19

Ring

7.4 ± 2.0

9.6 ± 3.1

9.2 ± 3.8

POH-ND

POH-ND

Trophozoite

30.4 ± 6.7

36.3 ± 6.1

25.6 ± 4.8

23.0 ± 3.5

POH-ND

Schizont

2.1 ± 0.2

0.9 ± 0.1

0.9 ± 0.2

1.1 ± 0.3

0.9 ± 0.2

  1. Ratios were calculated using the area of the signal corresponding to each metabolite normalized to the cell number. Values represent the mean ± s.e.m. from three independent biological replicates. POH-ND, polyprenol not detected under the experimental conditions used in this study.
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