Figure 7


Three-dimensional RSM plots for riboflavin production showing the effect of concentration of fructose, tryptone, K2HPO4 and CaCl2 and their mutual interaction in pairs when the other two variables were constant at zero level. Interactions of (A) fructose and tryptone, (B) fructose and K2HPO4, (C) fructose and CaCl2, (D) tryptone and K2HPO4, (E) tryptone and CaCl2, and (F) K2HPO4 and CaCl2.