Figure 1 | Scientific Reports

Figure 1

From: Prevalence of pathogenic variants in DNA damage response and repair genes in patients undergoing cancer risk assessment and reporting a personal history of early-onset renal cancer

Figure 1

Patient characteristics. (A) Age range of individuals diagnosed with RC ≤ 60 years in SEER cohort compared to the study cohort (n = 746; of the remaining individuals in the study, 26 were diagnosed < 19 years, 33 were diagnosed at 60 years, and 39 were excluded from the calculations as their age was reported as a wide range of years). (B) Percentage of males and females diagnosed with RC ≤ 60 years in SEER compared to the study cohort (n = 844). (C) The percentages of reported RC histology up to age 60 years in the SEER data (n = 97,805) compared to the study cohort (n = 844); not all histological subtypes reported in SEER were reported in the study cohort. (D) The percentage of cancer incidence (at ≤ 60 years) in the general SEER population versus the study cohort. The SEER data reflect individuals reporting the indicated cancer type, not individuals with RC in addition to the indicated cancer type. (E) Percentage of different primary cancers reported (≤ 60 years) in SEER (n = 97,795) versus the study cohort (n = 844). Less than 0.4% not reported for figure clarity.

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