Table 2 Transmission disequilibrium test for PLG variants in 314 US trios.

From: Multi-omic studies on missense PLG variants in families with otitis media

Variant

White

Hispanic

Black

Mixed/Other

Transmitted

Non-transmitted

TDT p

p.Lys38Glu

232

44

21

17

3

4

0.71

p.Arg261His

30

3

0

7

0

0

–

p.Ala494Val

49

7

2

9

0

1

0.31

p.Ile682Asn

190

41

22

10

1

0

0.32

p.Asp472Asn

221

44

23

17

101

116

0.31

All variants1

215

43

21

17

104

119

0.32

  1. 1For UTMB59, the father transmitted the minor allele for both c.112A > G (p.Lys38Glu) and c.1414G > A (p.Asp472Asn) variants to the child. On the other hand, for each of two trios UTMB132 and UTMB206 one parent carried both c.112A > G (p.Lys38Glu) and c.1414G > A (p.Asp472Asn) variants but did not transmit the minor alleles to the child.
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