Figure 1 | Scientific Reports

Figure 1

From: The ubiquitin ligase Cullin-1 associates with chromatin and regulates transcription of specific c-MYC target genes

Figure 1

Cullin gene expression in human cells. (A) Box plot comparison of cullin expression in 62 human tissues shows highest expression of CUL1 and CUL4B. (B) CUL1 and CUL3 are the most highly expressed cullins across 64 human cell lines. The y-axis depicts consensus normalized mRNA expression levels (“NX”) based on The Human Protein Atlas (v.19.3). (C) Cullin paralogs have unique functions despite a high degree of amino acid sequence similarity. CUL7 is the most divergent with a combined amino acid sequence identity and similarity of 53.4% compared to CUL1.

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