Table 3 Baseline DTI measures, reported as mean (standard deviation), for all RRMS patients according to CSF-OCB status.

From: Advanced MRI features in relapsing multiple sclerosis patients with and without CSF oligoclonal IgG bands

 

ALL (n = 67)

OCB-negative (n = 25)

OCB-positive (n = 42)

Adjusted p-value

Lesional area

FA

0.317 (0.056)

0.320 (0.406)

0.315 (0.063)

0.989

MD (× 10−3 mm2/s)

1.167 (0.202)

1.166 (0.117)

1.167 (0.202)

0.568

Perilesional NAWM

FA

0.372 (0.032)

0.376 (0.035)

0.370 (0.030)

0.383

MD (× 10−3 mm2/s)

1.150 (0.157)

1.113 (0.114)

1.173 (0.176)

0.043

Distal NAWM

FA

0.432 (0.024)

0.434 (0.029)

0.431 (0.021)

0.834

MD (× 10−3 mm2/s)

0.801 (0.110)

0.805 (0.040)

0.798 (0.136)

0.430

Corpus callosum

FA

0.474 (0.082)

0.468 (0.117)

0.478 (0.053)

0.775

MD (× 10−3 mm2/s)

1.081 (0.140)

1.054 (0.135)

1.097 (0.152)

0.390

  1. The difference of the means was calculated using ANCOVA, and adjusted for disease duration.
  2. All p-values were adjusted for multiple comparisons using the false discovery rate method.
  3. Significant p-values are shown in bold.
  4. CSF cerebrospinal fluid, OCB oligoclonal IgG bands, FA fractional anisotropy, MD mean diffusivity, NAWM normal appearing white matter.
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