Table 1 Top four genes carrying the highest number of enriched and depleted T2D-associated SNPs in various populations.
IR | AFR | AMR | EUR | SAS | EAS | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Gene | Count | Gene | Count | Gene | Count | Gene | Count | Gene | Count | Gene | Count | |
Enriched | TCF7L2 | 62 | TCF7L2 | 77 | TCF7L2 | 24 | TCF7L2 | 63 | TCF7L2 | 28 | CDKAL1 | 30 |
CDKAL1 | 4 | CDKAL1 | 33 | SLC16A11 | 19 | CDKN1C | 4 | IGF2BP2 | 14 | SLC16A11 | 13 | |
CDKN1C | 4 | IGF2BP2 | 31 | SLC16A13 | 3 | CDKAL1 | 1 | CDKN1C | 4 | CDKN2B | 2 | |
TECRL | 1 | SLC16A11 | 19 | HLA-DQA2 | 1 | TECRL | 1 | CDKAL1 | 1 | SLC16A13 | 2 | |
Depleted | IGF2BP2 | 30 | TCF7L2 | 30 | IGF2BP2 | 30 | IGF2BP2 | 31 | TCF7L2 | 32 | TCF7L2 | 75 |
SLC16A11 | 18 | CDKAL1 | 18 | TCF7L2 | 30 | CDKAL1 | 26 | SLC16A11 | 19 | IGF2BP2 | 30 | |
CDKAL1 | 16 | SLC16A11 | 12 | CDKAL1 | 29 | SLC16A11 | 17 | CDKAL1 | 17 | CDKN1C | 4 | |
TCF7L2 | 3 | CDKN1C | 2 | CDKN1C | 3 | SLC16A13 | 3 | SLC16A13 | 3 | SLC16A11 | 4 | |
