Table 2 The association of PRS with the prevalence of type 2 diabetes.

From: High genetic burden of type 2 diabetes can promote the high prevalence of disease: a longitudinal cohort study in Iran

Quintile

Sample size

PR (95% CI)

p-value

2 (20–40%)

713

0.9 (0.76, 1.1)

0.53

3 (40–60%)

638

1.05 (0.86, 1.2)

0.6

4 (60–80%)

826

1.34 (1.1, 1.6)

0.001

5 (> 80%)

631

1.44 (1.2, 1.7)

0.00006

  1. Prevalence ratio (PR) with 95% confidence intervals (95% CI) from robust Poisson regression analysis. The model is adjusted for age, sex, and BMI. The first quintile (< 20%) containing 766 individuals were considered as reference. The whole sample size was 3,574 individuals.