Figure 8 | Scientific Reports

Figure 8

From: A biphasic nanohydroxyapatite/calcium sulphate carrier containing Rifampicin and Isoniazid for local delivery gives sustained and effective antibiotic release and prevents biofilm formation

Figure 8

Cell material interactions. Murine pre-osteoblasts (MC3T3E1) grown on the surface of calcium sulphate hemihydrate (CSH)/nanohydroxyapatite (nHAP) based nanocement (NC) and drug loaded NC (drug@NC) for seven days. DAPI staining of cells at day 7 grown on (a) NC, (b) NC + INH, (c) NC + RFP and (d) NC + RFP + INH. Scanning electron micrograph (SEM) images of cells at day 7 grown on (e) NC, (f) NC + INH, (g) NC + RFP and (h) NC + RFP + INH, (i) MTT assay for seven days showing cell proliferation of cells and non-cytotoxicity of materials.

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