Table 2 Similar and different associations between dysregulation and GFA values between autism spectrum disorder (ASD) and typically developing controls (TDC) based on the main sample.
Pattern | Tract | Connected ROIs | Connected ROIs | System |
---|---|---|---|---|
Similar association | Not significant | |||
Different association | ||||
(a) The lower GFA values with the worse regulation in ASD/the better regulation in TDC | ||||
 | Left ILF | L_temporal pole | Occipital lobe | Emotion recognition and visual-affective integration |
Left UF | L_orbitofrontal gyrus | L_superior temporal pole | Emotion regulation | |
CC of genu | L_frontal components, including orbitofrontal gyrus | R_frontal components, including orbitofrontal gyrus | high cortical function regulation | |
(b) The higher GFA values with the worse regulation in ASD/the better regulation in TDC | ||||
 | L_CST of mouth | L_primary motor cortex of mouth component | Brain stem | Motor |
 | L_CST of toe | L_primary motor cortex of toe component | Brain stem | Motor |
 | L_CST of geniculate fibers | L_primary motor cortex of throat component | Brain stem | Motor |
 | L_CST of trunk | L_primary motor cortex of trunk component | Brain stem | Motor |
 | L_CST of hand | L_primary motor cortex of hand component | Brain stem | Motor |
 | R_CST of geniculate fibers | R_primary motor cortex of throat component | Brain stem | Motor |
 | R_CST of trunk | R_primary motor cortex of trunk component | Brain stem | Motor |
 | R_CST of toe | R_primary motor cortex of toe component | Brain stem | Motor |
 | L_TR of auditory nerve | L_thalamus | L_Heschl’s gyrus | Sensory processing |
 | L_TR of precentral gyrus | L_thalamus | L_precentral gyrus | Sensorimotor integration |
 | R_TR of postcentral gyrus | R_thalamus | R_postcentral gyrus | Sensory processing |
 | L_cingulum of hippocampal component | L_cingulate gyrus posterior part | L_hippocampus | Emotion, memory |
 | L_cingulum of the main body component | L_cingulate gyrus (anterior + middle part) | L_cingulate gyrus posterior part | Attention, emotion, cognitive control |
 | Posterior commissure | Dorsal aspect of the upper end of the cerebral aqueduct | Bilateral cerebral hemispheres | Pupillary light reflex and upward saccade, both related to automatic emotion perception |
 | R_frontal aslant tract | R_SMA | R_inferior frontal gyrus opercular part | Inhibition |
 | L_medial lemniscus | L_thalamus | Brain stem | Somatosensory |