Table 1 Minimum inhibitory concentration of sCur vis a vis native curcumin/vancomycin/meropenem/ciprofloxacin.

From: Making of water soluble curcumin to potentiate conventional antimicrobials by inducing apoptosis-like phenomena among drug-resistant bacteria

Isolates

Curcumin

Soluble curcumin

Vancomycin

Meropenem

Ciprofloxacin

MIC (µg/ml)

MBC (µg/ml)

MIC (µg/ml)

MBC (µg/ml)

MIC (µg/ml)

MBC (µg/ml)

MIC (µg/ml)

MBC (µg/ml)

MIC (µg/ml)

MBC (µg/ml)

Staphylococcus aureus (ATCC29213)

128

≥ 1,024

16

64

0.5

2

-

-

0.25

0.5

Staphylococcus aureus (MRSA, 2,862/2019)

256

≥ 1,024

32

128

1

2

-

-

32

64

Staphylococcus epidermidis (ATCC35984)

128

≥ 1,024

16

32

0.25

1

-

-

 < 0.25

0.5

Klebsiella pneumoniae (ATCC700603)

256

≥ 1,024

32

128

256

≥ 1,024

0.5

1

0.5

1

Klebsiella pneumoniae (10,825/2019)

512

≥ 1,024

32

256

512

≥ 1,024

128

256

64

128

Escherichia coli (ATCC25922)

256

≥ 1,024

32

128

256

≥ 1,024

0.25

1

0.25

0.5

Escherichia coli (507/2019)

512

≥ 1,024

32

128

512

≥ 1,024

64

128

32

64

Pseudomonas aeruginosa (ATCC25619)

512

≥ 1,024

32

256

1,024

≥ 1,024

0.5

1

0.5

1

Pseudomonas aeruginosa (2,412/2019)

≥ 1,024

≥ 1,024

64

256

1,024

≥ 1,024

128

256

64

256