Table 1 Minimum inhibitory concentration of sCur vis a vis native curcumin/vancomycin/meropenem/ciprofloxacin.
Isolates | Curcumin | Soluble curcumin | Vancomycin | Meropenem | Ciprofloxacin | |||||
---|---|---|---|---|---|---|---|---|---|---|
MIC (µg/ml) | MBC (µg/ml) | MIC (µg/ml) | MBC (µg/ml) | MIC (µg/ml) | MBC (µg/ml) | MIC (µg/ml) | MBC (µg/ml) | MIC (µg/ml) | MBC (µg/ml) | |
Staphylococcus aureus (ATCC29213) | 128 | ≥ 1,024 | 16 | 64 | 0.5 | 2 | - | - | 0.25 | 0.5 |
Staphylococcus aureus (MRSA, 2,862/2019) | 256 | ≥ 1,024 | 32 | 128 | 1 | 2 | - | - | 32 | 64 |
Staphylococcus epidermidis (ATCC35984) | 128 | ≥ 1,024 | 16 | 32 | 0.25 | 1 | - | - | < 0.25 | 0.5 |
Klebsiella pneumoniae (ATCC700603) | 256 | ≥ 1,024 | 32 | 128 | 256 | ≥ 1,024 | 0.5 | 1 | 0.5 | 1 |
Klebsiella pneumoniae (10,825/2019) | 512 | ≥ 1,024 | 32 | 256 | 512 | ≥ 1,024 | 128 | 256 | 64 | 128 |
Escherichia coli (ATCC25922) | 256 | ≥ 1,024 | 32 | 128 | 256 | ≥ 1,024 | 0.25 | 1 | 0.25 | 0.5 |
Escherichia coli (507/2019) | 512 | ≥ 1,024 | 32 | 128 | 512 | ≥ 1,024 | 64 | 128 | 32 | 64 |
Pseudomonas aeruginosa (ATCC25619) | 512 | ≥ 1,024 | 32 | 256 | 1,024 | ≥ 1,024 | 0.5 | 1 | 0.5 | 1 |
Pseudomonas aeruginosa (2,412/2019) | ≥ 1,024 | ≥ 1,024 | 64 | 256 | 1,024 | ≥ 1,024 | 128 | 256 | 64 | 256 |