Figure 1

Effect of aerobic exercise training type on voluntary exercise capacity in ApoE−/− mice with LEAD. Quantification of total running distance during 24 h (24 h-TRD) at baseline and at the study endpoint. Data represent mean ± SEM (n = 10 in SED; n = 8 in FTR, n = 10 in VWR, and n = 10 in FS). Data were analyzed using two-way repeated measures ANOVA with Bonferroni’s post-hoc test: **P < 0.01, ***P < 0.001 vs. baseline. In this and the following figures: SED sedentary controls, FTR forced treadmill running, VWR voluntary wheel running, FS forced swimming.