Table 1 Bilayer nanomechanical resistance of the different SPB under study.

From: C24:0 and C24:1 sphingolipids in cholesterol-containing, five- and six-component lipid membranes

  

Breakthrough force (nN)

Continuous phase

Segregated domains

DOPC:lSM:Chol

+ lCer

7.0 ± 2.3

54.5 ± 12.0

+ nCer

4.8 ± 2.1

15.2 ± 1.2

+ lCer + nCer

2.3 ± 0.9

10.38 ± 1.57

16.38 ± 1.36

DOPC:nSM:Chol

+ lCer

4.1 ± 1.7

23.3 ± 6.9

 + nCer

1.5 ± 0.6

6.2 ± 2.4

 + lCer + nCer

2.0 ± 0.7

9.6 ± 1.9

DOPC:lSM:nSM:Chol

 + lCer

3.7 ± 1.9

31.9 ± 4.5

 + nCer

2.3 ± 0.8

7.2 ± 1.7

 + lCer + nCer

2.6 ± 1.9

11.3 ± 2.2

  1. Data expressed as mean ± SD, n = 300–1,000.