Table 1 Genotypes of the progeny from the Srsf6+/ intercross.

From: Silencing Srsf6 does not modulate incomplete splicing of the huntingtin gene in Huntington’s disease models

Genotype

Progeny observed

Percentage

Hypothesis 1 expected values (Srsf6−/− viable)

Hypothesis 2 expected values (Srsf6−/− inviable)

WT

9 (4 m, 5f.)

32.1%

7 (25%)

9.33 (33.3%)

Srsf6+/−

19 (9 m, 10f.)

67.9%

14 (50%)

18.66 (66.7%)

Srsf6−/−

0

0%

7 (25%)

0 (0%)

Statistics

Χ2

  

9.357

0.018

Degrees of freedom

  

2

1

p-value

  

0.009

0.895

Statistical significance?

  

Yes—distributions different

No—distributions the same