Table 4 Thermodynamic parameters for the various PLGA-PEG microspheres.

From: Drug-encapsulated blend of PLGA-PEG microspheres: in vitro and in vivo study of the effects of localized/targeted drug delivery on the treatment of triple-negative breast cancer

Formulations

Temperature (°C/K)

Ea (kJ mol−1)

ΔS (kJ mol−1 K−1)

ΔH (kJ mol−1)

ΔG (kJ mol−1)

PLGA-PEG_PGS

37/310.15

6.720

 − 0.170

6.720

52.871

41/314.15

53.553

44/317.15

54.064

PLGA-PEG_PGS-LHRH

37/310.15

4.379

 − 0.178

4.379

59.586

41/314.15

60.298

44/317.15

60.832

PLGA-PEG_PTX

37/310.15

7.714

 − 0.163

7.714

58.268

41/314.15

58.920

44/317.15

59.409

PLGA-PEG_PTX-LHRH

37/310.15

5.444

 − 0.170

5.444

58.170

41/314.15

58.850

44/317.15

59.360

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