Figure 4

The results of the non-negative matrix factorization procedure applied to the Raman spectra of the skin. (A–D) Output spectral components, obtained from the factorization procedure. (E,F) Typical depth profiles of the amplitudes of decomposition components for the volunteers with skin type II (E) and skin type III after sunlight exposure (F). Vertical dashed line in (E,F) indicates the position of the dermal–epidermal junction. The spectral components and amplitude profiles are normalized by their maximum value for visibility.