Table 1 Baseline characteristics expressed based on the total study population or stratified by median of serum MDK (n = 499).

From: Serum Midkine, estimated glomerular filtration rate and chronic kidney disease-related events in elderly women: Perth Longitudinal Study of Aging Women

 

All participants

MDK below median

MDK above median

p value

Number

499

250

249

 

MDK, pg/mL

437 [328, 580]

329 [278, 387]

579 [491, 784]

 

Age, years

75 [73, 77]

75 [73, 77]

75 [73, 78]

0.215

BMI, kg/m2

26.7 [24.0, 29.9]

27.1 [24.6, 30.3]

26.5 [23.3, 29.7]

0.097

Calcium treatment

257 (51.5)

136 (54.4)

121 (48.6)

0.194

Diabetes

34 (6.8)

13 (5.2)

21 (8.4)

0.152

Use of blood pressure lowering medication

229 (45.9)

110 (44.0)

119 (47.8)

0.395

Use of statin

90 (18.0)

43 (17.2)

47 (18.9)

0.626

Prevalent ASVD

69 (13.8)

31 (12.4)

38 (15.3)

0.355

Baseline CKD-EPI eGFR, mL/min/1.73m2a 

65.1 ± 12.7

65.4 ± 12.4

64.8 ± 13.0

0.605

Serum creatinine, mg/dL

0.90 ± 0.18

0.89 ± 0.17

0.90 ± 0.19

0.531

Serum cystatin C, mg/dL

1.07 ± 0.22

1.07 ± 0.21

1.08 ± 0.23

0.562

  1. Results are expressed as mean ± SD, median and [IQR], or number and (%).
  2. SD standard deviation, IQR interquartile range, MDK Midkine, BMI body mass index, ASVD atherosclerotic vascular disease, CKD-EPI eGFR Chronic Kidney Disease Epidemiology Collaboration estimated glomerular filtration rate.
  3. aMeasured in 422 participants using the CKD-EPI creatinine and cystatin C equation.
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