Table 2 Unadjusted and multivariable-adjusted Cox proportional hazard analysis of serum MDK in predicting 14.5-year CKD-related hospitalisations and deaths in elderly women.

From: Serum Midkine, estimated glomerular filtration rate and chronic kidney disease-related events in elderly women: Perth Longitudinal Study of Aging Women

 

MDK below median (< 437 pg/mL)

MDK above median (≥ 437 pg/mL)

p value

Number of events (%)

18 (7.2)

29 (11.6)

 

Unadjusted HR (95% CI)

1.00 (referent)

1.82 (1.01, 3.28)

0.046

Multivariable-adjusted HR (95% CI)

1.00 (referent)

1.72 (0.96, 3.11)

0.071

Multivariable and baseline eGFR-adjusted HR (95% CI)

1.00 (referent)

1.27 (0.66, 2.46)

0.470

  1. Multivariable model was adjusted for age, calcium treatment code, diabetes and prevalent atherosclerotic vascular disease.
  2. MDK Midkine, CKD chronic kidney disease, eGFR estimated glomerular filtration rate, HR hazard ratio, CI confidence interval.
  3. Bold indicates statistical significance of the p value.
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