Figure 6
RFX5-KDM4A pathway promotes cell cycle transition in HCC. HCC cells with different treatment were subjected to FACS analysis with anti-BrdU and 7AAD staining to measure the cell cycle transition. (A–D) MHCC-97H (A,B) and HepG2 (C,D) cells transduced with the control lentiviral vector, FLAG-RFX5 or KDM4A were subjected to cell cycle analysis (A,C) and One-way ANOVA analysis (B,D). (E–H) MHCC-97H (E,F) and HepG2 (G,H) cells transduced with lentiviral sgRNA targeting RFX5 together with the control retroviral vector or KDM4A were subjected to cell cycle analysis (E,G) and One-way ANOVA analysis (F,H). **P < 0.01, ***P < 0.001.
