Figure 3

Graphic representation of results from the H3K27ac ChIP-Seq and ATAC-Seq analyses in MSY regions. Results represent those obtained within the genomic regions of the Uty locus and its two flanking genes. RefSeq gene coordinates are shown on top. Peaks for either H3K27ac ChIP-Seq or ATAC-Seq are shown in either the top or bottom framed areas, respectively. The areas framed in green indicate highlight peaks detected in WT, but not in UtyGT mice. All detected peaks align with those published by ENCODE (in red) and obtained using extracts from adult mouse hearts for either H3K27ac, p300 or Pol2 ChIP-Seq or Dnase hypersensitivity assays.