Table 2 Univariate logistic regression analysis of the predictor of Colorectal Cancer.

From: A clinical prediction nomogram to assess risk of colorectal cancer among patients with type 2 diabetes

Variable

β

Odds ratio (95% CI)

P value

Age, years

0.043

1.044 (1.023–1.066)

< 0.001

Duration of diabetes, month

0.003

1.003 (1.000–1.005)

0.041

Family history of colorectal cancer

0.132

1.141 (0.722–1.805)

0.572

Sex

− 1.392

0.249 (0.151–0.410)

< 0.001

BMI, kg/m2

− 0.082

0.922 (0.914–0.929)

< 0.001

Smoking, yes

0.196

1.217(0.817–1.814)

0.335

Blood-glucose-lowering drugs

Insulin, yes

0.371

1.449 (0.908–2.311)

0.119

Thiazolidinediones, yes,

1.728

5.627 (2.055–15.409)

0.001

Alpha glucosidase inhibitors, yes,

0.367

1.444 (0.835–2.497)

0.188

Sulfonylureas, yes

− 0.503

0.605 (0.315–1.159)

0.130

Metformin, yes,

0.418

1.519 (0.957–2.412)

0.076

Other blood-glucose-lowering drugs

0.545

1.724 (1.044–2.846)

0.033

Combination of oral drugs and insulin, yes

0.405

1.500 (0.608–3.703)

0.379

Combination oforal drugs, yes

0.518

1.679 (0.989–2.851)

0.055

  1. Other blood-glucose-lowering drugs: defined as Chinese medicine or proprietary Chinese medicine of blood-glucose-lowering drugs.
  2. No patients in our study cohort used DPP-4 inhibitors, GLP-1 receptor agonists and SGLT2 inhibitors.
  3. BMI body mass index.
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