Figure 1

Characterization of type1 and type2 NI in NAFLD. The images show two representative HE-stainings of tissue sections from type1 and type2 NI demonstrating that type1 NI are surrounded by a basophilic membrane, which is lacking in type2 NI. Positive PAS staining is detected both for type1 and type2 NI and the negative staining for PAS diastase depicts glycogen accumulation as the origin for this positivity. Immunofluorescence analysis on lamin AC expression demonstrates that lamin AC is at the membrane bordering type1 NI. The white bar at the bottom right, representative for all images indicates 10 µm. Original magnifications: 1,000 X.