Figure 2

Associations between the number of NI and disease progression. (a) Number of type1 NI/1,000 cells increases with progression of NAFLD; NASH vs. controls: ***P < 0.001; NASH vs. NAFL: *P = 0.012; NAFL vs. controls: *P = 0.016. Number of type1 NI/1,000 cells: Control 0.06 (0–0.21), NAFL 0.26 (0–2.19), NASH 1.15 (0–10). (b) Type2 NI/1,000 cells are more in NASH than in controls: ***P = 0.001. Number of type2 NI/1,000 cells: Control 0.17 (0–14.96), NAFL 0.26 (0–38.25), NASH 4.03 (0–78.49); values are medians with ranges presented in parentheses. (All Kruskal–Wallis test; bold lines inside the box plot represent median levels; the values are shown). Results are significant at *P ≤ 0.05 and ***P ≤ 0.001.